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Bazil Lab

The Bazil lab is focused on the study of cardiac energetics and how it is impacted by heart disease and ischemia/reperfusion injury. We implement both experimental and computational models to analyze how changes in energetic demand, substrate supply, and oxidative stress alter cellular and mitochondrial physiology.

Meet the Team!

Dr. Jason Bazil, PI
Alyssa Vadovsky, graduate student
Jada Roberts, graduate student
Keeler Steele, graduate student
Desire Tuohy, undergraduate student
Joseph Kesto, undergraduate student
Kieran Doran, undergraduate student
Lawand Barwary, undergraduate student
Tianyi Xia, undergraduate student

Recent Publications

Our team is dedicated to advancing the understanding of mitochondrial function, cardiovascular health, and related physiological processes. Below are some of our recent publications. For a complete list, please visit our publications page.

Recent Publications from Our Lab

Visker JR, Leszczynski EC, Wellette-Hunsucker AG, McPeek AC, Quinn MA, Kim SH, Bazil JN, Ferguson DP. Postnatal growth restriction alters myocardial mitochondrial energetics in mice. Exp Physiol. 2024 Apr;109(4):562-575. doi: 10.1113/EP091304. Epub 2024 Jan 5. PMID: 38180279; PMCID: PMC10984791.
Chapa-Dubocq XR, Rodríguez-Graciani KM, García-Báez J, Vadovsky A, Bazil JN, Javadov S. The Role of Swelling in the Regulation of OPA1-Mediated Mitochondrial Function in the Heart In Vitro. Cells. 2023 Aug 8;12(16):2017. doi: 10.3390/cells12162017. PMID: 37626827; PMCID: PMC10453793.
Banga S, Abela GS, Saltiel F, Fischell T, Kalavakunta JK, Sood A, Jolly G, Najib K, Al-Ali H, Qintar M, Bazil J, Singh Y, Gupta V. Management of Atrial Fibrillation Post Transcatheter Aortic Valve Implantation. Am J Cardiol. 2023 Aug 1;200:171-177. doi: 10.1016/j.amjcard.2023.05.024. Epub 2023 Jun 15. PMID: 37329837.
Walkon LL, Strubbe-Rivera JO, Bazil JN. https://pubmed.ncbi.nlm.nih.gov/36551319/. Biomolecules. 2022 Dec 17;12(12):1891. doi: 10.3390/biom12121891. PMID: 36551319; PMCID: PMC9775684.