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Douglas Luckie, Ph.D.

Douglas B. Luckie, CF Research Lab – Molecular Physiology Research:

Luckie's research program has involved questions ranging from, the reason for pH changes that occur in cystic fibrosis, how to best diagnose CF with molecular assays, as well as the impact of "correctors" used in treatment of the disease.

The research projects were in collaborations with faculty in Physiology: Drs. Root-Bernstein, Busik, and Olson, in Art: Dr. Adam Brown, faculty in Microbiology: Drs. Martha Mulks & Terry Marsh, as well as Plant Pathology, Dr. George Sundin and Jeanette Jacobs.

Douglas B. Luckie STEM Learning Lab – Education Research:
Luckie serves as the principal investigator of the “STEM Learning lab" which employs undergraduates, graduate students, postdocs and collaborating faculty who pursue biology/physiology education research. Our research group examines how theoretically grounded experimental approaches in teaching can increase student learning in science.

This research program led to collaborations with a range of faculty in several units including Drs. Ryan Sweeder in Lyman Briggs, Brian O’Shea in Physics & Astronomy, Richard Bellon in History, Tammy Long and Diane Ebert-May in Department of Plant Biology.

Selected Publications

M.K. Massey, Reiterman M.J., Mourad J. and Luckie D.B. (2021) Is CFTR an exchanger?: Regulation of HCO3- Transport and extracellular pH by CFTR. Biochemistry and Biophysics Reports, 25: (in press).

M.R. Cederman, Leff M.F., Monforton M.R., Bauer A.M. and Luckie D.B. (2020) Identification of G551D-CFTR allele via AS-PCR of buccal cells. Current Topics in Biochemical Research, 21: 15-23

D.B. Luckie, Mancini, B.W., Abdullah, N., Kadouh, A.K., Ungkuldee, A.C.P. and Hare A.A. (2020) Undergraduate TAs can provide strong support for reformed practices to raise student learning. Advances in Physiology Education, 44: 32–38.

D.B. Luckie, Hoskinson, A.M., Griffin C.E., Hess A.L, Price, K.J., Tawa, A. & Thacker S.M. (2017). Integrating concepts in biology textbook increases learning: assessment triangulation using concept inventory, card sorting, and MCAT instruments, followed by longitudinal tracking. CBE-Life Science Education, (16)20, 1-10.

S.A. Valles, Luckie, D.B., Montgomery, G.M., Simmons, E.H., Sweeder R.D., & Zeleke A. (2016). Updating the two cultures: how structures can promote interdisciplinary cultures. Change: Magazine of Higher Learning, (48)6, 28-35.

D.B. Luckie, Van Alst AJ, Massey MK, Flood RD, Shah AA, Malhotra V, Kozel BJ. (2014) Chemical rescue of ΔF508-CFTR in C127 epithelial cells reverses aberrant extracellular pH acidification to wildtype alkalization as monitored by microphysiometry. Biochem Biophys Res Commun., 451: 535-40.

*D.B. Luckie, J.R. Aubry, A.M. Rivkin, B.J. Marengo, L.A. Foos and J.J. Maleszewski (2012) Less teaching, more learning: A 10-year study supports increases in inquiry alongside decreases in “coverage” yield steady gains in student learning of science. Advances in Physiology Education 36: 325–335. *Selected as “Editor’s Pick” of the American Physiology Society.

D.B. Luckie, M.E. Krouse (2012) Cystic Fibrosis: Does CFTR Malfunction Alter pH Malfunction? Genetic Disorders (12): 319-344.

D.B. Luckie, R. Bellon, and R.D. Sweeder (2012) The “BRAID”: Experiments in Stitching Together Disciplines at a Big 10 University, Journal of STEM Education 13(2): 6-14.

D.B. Luckie, J.R. Aubry, A.M. Rivkin, (2013) Verbal final exam in introductory biology yields gains in student content knowledge and longitudinal performance. CBE-Life Sciences Education (submitted in January 2012, Accepted in June 2012, in press).

Main Office
Department of Physiology
 Biomedical Physical Sciences (BPS) Building
567 Wilson Rd Rm 2201
Main Phone: 517-884-5000

Department Chairperson

Dr. Charles "Lee" Cox
Dr. Charles "Lee" Cox
BPS Building Rm 2201E
Phone: 517-884-5050

MSU Research Integrity Officer
Wills House
287 Delta Court, Room 106
Phone: 517-432-6698
Research Integrity Office